Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma

Here, we use a mouse model (DBA/2J) to readdress the location of insult(s) to retinal ganglion cells (RGCs) in glaucoma. We localize an early sign of axon damage to an astrocyte-rich region of the optic nerve just posterior to the retina, analogous to the lamina cribrosa. In this region, a network o...

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Detalles Bibliográficos
Autores principales: Howell, Gareth R., Libby, Richard T., Jakobs, Tatjana C., Smith, Richard S., Phalan, F. Campbell, Barter, Joseph W., Barbay, Jessica M., Marchant, Jeffrey K., Mahesh, Nagaraju, Porciatti, Vittorio, Whitmore, Alan V., Masland, Richard H., John, Simon W. M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373494/
https://www.ncbi.nlm.nih.gov/pubmed/18158332
http://dx.doi.org/10.1083/jcb.200706181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373494/
https://www.ncbi.nlm.nih.gov/pubmed/18158332
http://dx.doi.org/10.1083/jcb.200706181

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