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Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells

To determine how extracellular signal–regulated kinases (ERK) 1/2 promote mammary tumorigenesis, we examined the real-time behavior of cells in an organotypic culture of the mammary glandular epithelium. Inducible activation of ERK1/2 in mature acini elicits cell motility and disrupts epithelial arc...

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Detalles Bibliográficos
Autores principales: Pearson, Gray W., Hunter, Tony
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373504/
https://www.ncbi.nlm.nih.gov/pubmed/18166657
http://dx.doi.org/10.1083/jcb.200706099