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Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells
To determine how extracellular signal–regulated kinases (ERK) 1/2 promote mammary tumorigenesis, we examined the real-time behavior of cells in an organotypic culture of the mammary glandular epithelium. Inducible activation of ERK1/2 in mature acini elicits cell motility and disrupts epithelial arc...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373504/ https://www.ncbi.nlm.nih.gov/pubmed/18166657 http://dx.doi.org/10.1083/jcb.200706099 |