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The histone methyltransferase SET8 is required for S-phase progression

Chromatin structure and function is influenced by histone posttranslational modifications. SET8 (also known as PR-Set7 and SETD8) is a histone methyltransferase that monomethylates histonfe H4-K20. However, a function for SET8 in mammalian cell proliferation has not been determined. We show that sma...

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Detalles Bibliográficos
Autores principales: Jørgensen, Stine, Elvers, Ingegerd, Trelle, Morten Beck, Menzel, Tobias, Eskildsen, Morten, Jensen, Ole Nørregaard, Helleday, Thomas, Helin, Kristian, Sørensen, Claus Storgaard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373509/
https://www.ncbi.nlm.nih.gov/pubmed/18166648
http://dx.doi.org/10.1083/jcb.200706150