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The many faces of ubiquitinated histone H2A: insights from the DUBs

Monoubiquitination of H2A is a major histone modification in mammalian cells. Understanding how monoubiquitinated H2A (uH2A) regulates DNA-based processes in the context of chromatin is a challenging question. Work in the past years linked uH2A to transcriptional repression by the Polycomb group pro...

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Detalles Bibliográficos
Autores principales: Vissers, Joseph HA, Nicassio, Francesco, van Lohuizen, Maarten, Di Fiore, Pier Paolo, Citterio, Elisabetta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373781/
https://www.ncbi.nlm.nih.gov/pubmed/18430235
http://dx.doi.org/10.1186/1747-1028-3-8