Gpnmb(R150X )allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma

BACKGROUND: The Gpnmb gene encodes a transmembrane protein whose function(s) remain largely unknown. Here, we assess if a mutant allele of Gpnmb confers susceptibility to glaucoma by altering immune functions. DBA/2J mice have a mutant Gpnmb gene and they develop a form of glaucoma preceded by a pig...

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Detalles Bibliográficos
Autores principales: Anderson, Michael G, Nair, K Saidas, Amonoo, Leslie A, Mehalow, Adrienne, Trantow, Colleen M, Masli, Sharmila, John, Simon WM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373794/
https://www.ncbi.nlm.nih.gov/pubmed/18402690
http://dx.doi.org/10.1186/1471-2156-9-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373794/
https://www.ncbi.nlm.nih.gov/pubmed/18402690
http://dx.doi.org/10.1186/1471-2156-9-30

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