Microphthalmia and cataract in rats with a novel point mutation in connexin 50 - L7Q

PURPOSE: We isolated an autosomal semi-dominant cataract from our inbred SHR/OlaIpcv rat colony. Heterozygotes express pulverulent cataract with smaller eyes; homozygotes express marked microphthalmia with hypoplastic lens. We call this mutation Dca (for dominant cataract). In this study, we focus o...

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Detalles Bibliográficos
Autores principales: Liška, František, Chylíková, Blanka, Martínek, Jindřich, Křen, Vladimír
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373795/
https://www.ncbi.nlm.nih.gov/pubmed/18470322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373795/
https://www.ncbi.nlm.nih.gov/pubmed/18470322

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