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Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation

We identify the tumor necrosis factor receptor superfamily 25 (TNFRSF25)/TNFSF15 pair as critical trigger for allergic lung inflammation, which is a cardinal feature of asthma. TNFRSF25 (TNFR25) signals are required to exert T helper cell 2 (Th2) effector function in Th2-polarized CD4 cells and co-s...

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Detalles Bibliográficos
Autores principales: Fang, Lei, Adkins, Becky, Deyev, Vadim, Podack, Eckhard R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373837/
https://www.ncbi.nlm.nih.gov/pubmed/18411341
http://dx.doi.org/10.1084/jem.20072528