Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene

The maintenance of memory T cells is central to the establishment of immunological memory, although molecular details of the process are poorly understood. In the absence of the polycomb group (PcG) gene Bmi1, the number of memory CD4(+) T helper (Th)1/Th2 cells was reduced significantly. Enhanced c...

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Detalles Bibliográficos
Autores principales: Yamashita, Masakatsu, Kuwahara, Makoto, Suzuki, Akane, Hirahara, Kiyoshi, Shinnaksu, Ryo, Hosokawa, Hiroyuki, Hasegawa, Akihiro, Motohashi, Shinichiro, Iwama, Atsushi, Nakayama, Toshinori
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373843/
https://www.ncbi.nlm.nih.gov/pubmed/18411339
http://dx.doi.org/10.1084/jem.20072000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373843/
https://www.ncbi.nlm.nih.gov/pubmed/18411339
http://dx.doi.org/10.1084/jem.20072000

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