Cargando…

Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene

The maintenance of memory T cells is central to the establishment of immunological memory, although molecular details of the process are poorly understood. In the absence of the polycomb group (PcG) gene Bmi1, the number of memory CD4(+) T helper (Th)1/Th2 cells was reduced significantly. Enhanced c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamashita, Masakatsu, Kuwahara, Makoto, Suzuki, Akane, Hirahara, Kiyoshi, Shinnaksu, Ryo, Hosokawa, Hiroyuki, Hasegawa, Akihiro, Motohashi, Shinichiro, Iwama, Atsushi, Nakayama, Toshinori
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373843/ https://www.ncbi.nlm.nih.gov/pubmed/18411339 http://dx.doi.org/10.1084/jem.20072000

Ejemplares similares

Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells
por: Hosokawa, Hiroyuki, et al.
Publicado: (2016)

STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells
por: Onodera, Atsushi, et al.
Publicado: (2010)

Repression of Noxa by Bmi1 contributes to deguelin‐induced apoptosis in non‐small cell lung cancer cells
por: Li, Wei, et al.
Publicado: (2018)

Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation
por: Suzuki, Akane S., et al.
Publicado: (2020)

Regulation of T helper type 2 cell differentiation by murine Schnurri-2
por: Kimura, Motoko Y., et al.
Publicado: (2005)

A Novel Small Compound SH-2251 Suppresses Th2 Cell-Dependent Airway Inflammation through Selective Modulation of Chromatin Status at the Il5 Gene Locus
por: Suzuki, Junpei, et al.
Publicado: (2013)

Conventional and pathogenic Th2 cells in inflammation, tissue repair, and fibrosis
por: Kokubo, Kota, et al.
Publicado: (2022)

Activated iNKT cells enhance the anti-tumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer
por: Makita, Yuji, et al.
Publicado: (2018)

Maintenance of memory-type pathogenic Th2 cells in the pathophysiology of chronic airway inflammation
por: Hirahara, Kiyoshi, et al.
Publicado: (2018)

The Role of CD4(+) Resident Memory T Cells in Local Immunity in the Mucosal Tissue – Protection Versus Pathology –
por: Hirahara, Kiyoshi, et al.
Publicado: (2021)

The Menin–Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis
por: Kuwahara, Makoto, et al.
Publicado: (2014)

Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis
por: Fujimoto, Masanori, et al.
Publicado: (2022)

Activated invariant natural killer T cells directly recognize leukemia cells in a CD1d‐independent manner
por: Aoki, Takahiro, et al.
Publicado: (2020)

Discrepant NOXA (PMAIP1) transcript and NOXA protein levels: a potential Achilles' heel in mantle cell lymphoma
por: Dengler, M A, et al.
Publicado: (2014)

Pathogenic Impacts of Dysregulated Polycomb Repressive Complex Function in Hematological Malignancies
por: Kaito, Satoshi, et al.
Publicado: (2020)

NOXA as critical mediator for drug combinations in polychemotherapy
por: Ehrhardt, H, et al.
Publicado: (2012)

Blockade of programmed death-1/programmed death ligand pathway enhances the antitumor immunity of human invariant natural killer T cells
por: Kamata, Toshiko, et al.
Publicado: (2016)

HDAC inhibitors repress the polycomb protein BMI1
por: Grant, Steven
Publicado: (2010)

Invariant NKT cells are resistant to circulating CD15(+) myeloid‐derived suppressor cells in patients with head and neck cancer
por: Horinaka, Atsushi, et al.
Publicado: (2016)

Aspirin Induced Glioma Apoptosis through Noxa Upregulation
por: Chang, Cheng-Yi, et al.
Publicado: (2020)

NOXA Is Important for Verticillium dahliae’s Penetration Ability and Virulence
por: Zhu, Xiaohan, et al.
Publicado: (2021)

Genome-Wide Gene Expression Profiling Revealed a Critical Role for GATA3 in the Maintenance of the Th2 Cell Identity
por: Sasaki, Tetsuya, et al.
Publicado: (2013)

Immune Cell-Epithelial/Mesenchymal Interaction Contributing to Allergic Airway Inflammation Associated Pathology
por: Hirahara, Kiyoshi, et al.
Publicado: (2019)

The Cxxc1 subunit of the Trithorax complex directs epigenetic licensing of CD4(+) T cell differentiation
por: Kiuchi, Masahiro, et al.
Publicado: (2021)

Thioredoxin-interacting protein is essential for memory T cell formation via the regulation of the redox metabolism
por: Kokubo, Kota, et al.
Publicado: (2023)

Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
por: Nakajima-Takagi, Yaeko, et al.
Publicado: (2023)

Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation
por: Karim, Christine B., et al.
Publicado: (2015)

Memory-type ST2(+)CD4(+) T cells participate in the steroid-resistant pathology of eosinophilic pneumonia
por: Mato, Naoko, et al.
Publicado: (2017)

Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro
por: Nomura, Shunsuke, et al.
Publicado: (2019)

A Novel Zinc Finger Protein Zfp277 Mediates Transcriptional Repression of the Ink4a/Arf Locus through Polycomb Repressive Complex 1
por: Negishi, Masamitsu, et al.
Publicado: (2010)

Relationship between BMI and Postoperative Complications with Free Flap in Anterolateral Craniofacial Reconstruction
por: Heo, Yang Hoi, et al.
Publicado: (2016)

The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression
por: Lynch, James T, et al.
Publicado: (2010)

Expression of Bim, Noxa, and Puma in non-small cell lung cancer
por: Sakakibara-Konishi, Jun, et al.
Publicado: (2012)

BAK and NOXA Are Critical Determinants of Mitochondrial Apoptosis Induced by Bortezomib in Mesothelioma
por: Busacca, Sara, et al.
Publicado: (2013)

Harnessing Noxa demethylation to overcome Bortezomib resistance in mantle cell lymphoma
por: Leshchenko, Violetta V., et al.
Publicado: (2015)

Erratum: Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation
por: Karim, Christine B., et al.
Publicado: (2015)

BIM and NOXA are mitochondrial effectors of TAF6δ-driven apoptosis
por: Delannoy, Aurélie, et al.
Publicado: (2018)

SAT-300 Evading Death: Noxa in Cushing’s Disease Pituitary Adenomas
por: Alvarez, Reinier, et al.
Publicado: (2020)

Unmasking BCL-2 Addiction in Synovial Sarcoma by Overcoming Low NOXA
por: Fairchild, Carter K., et al.
Publicado: (2021)

Pituitary adenomas evade apoptosis via noxa deregulation in Cushing’s disease
por: Asuzu, David T., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_41lv8dpljk8s7r23qqfchtot0g