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Scaffolding and validation of bacterial genome assemblies using optical restriction maps

Motivation: New, high-throughput sequencing technologies have made it feasible to cheaply generate vast amounts of sequence information from a genome of interest. The computational reconstruction of the complete sequence of a genome is complicated by specific features of these new sequencing technol...

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Detalles Bibliográficos
Autores principales: Nagarajan, Niranjan, Read, Timothy D., Pop, Mihai
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373919/
https://www.ncbi.nlm.nih.gov/pubmed/18356192
http://dx.doi.org/10.1093/bioinformatics/btn102