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An improved physico-chemical model of hybridization on high-density oligonucleotide microarrays

Motivation: High-density DNA microarrays provide useful tools to analyze gene expression comprehensively. However, it is still difficult to obtain accurate expression levels from the observed microarray data because the signal intensity is affected by complicated factors involving probe–target hybri...

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Detalles Bibliográficos
Autores principales: Ono, Naoaki, Suzuki, Shingo, Furusawa, Chikara, Agata, Tomoharu, Kashiwagi, Akiko, Shimizu, Hiroshi, Yomo, Tetsuya
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373920/
https://www.ncbi.nlm.nih.gov/pubmed/18378525
http://dx.doi.org/10.1093/bioinformatics/btn109