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Detection of micrometastasis by cytokeratin 20 RT-PCR is limited due to stable background transcription in granulocytes

The reverse transcription polymerase chain reaction (RT-PCR) amplification of cytokeratin 20 (CK20) mRNA is considered a promising candidate method for the detection of circulating tumour cells in bone marrow and peripheral blood of cancer patients. In this study we have investigated the diagnostic...

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Detalles Bibliográficos
Autores principales: Jung, R, Petersen, K, Krüger, W, Wolf, M, Wagener, C, Zander, A, Neumaier, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374287/
https://www.ncbi.nlm.nih.gov/pubmed/10555760
http://dx.doi.org/10.1038/sj.bjc.6690778