Differential expression of topoisomerase I and RAD52 protein in yeast reveals new facets of the mechanism of action of bisdioxopiperazine compounds

A screening procedure which permits identification of compounds based on their activities against specific biological targets directly in a living organism, Saccharomyces cerevisiae, has been established as part of our new drug discovery programme. Use of this assay has provided the first direct evi...

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Detalles Bibliográficos
Autores principales: Hille, B van, Clerc, X, Creighton, A M, Hill, B T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374289/
https://www.ncbi.nlm.nih.gov/pubmed/10555749
http://dx.doi.org/10.1038/sj.bjc.6690767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374289/
https://www.ncbi.nlm.nih.gov/pubmed/10555749
http://dx.doi.org/10.1038/sj.bjc.6690767

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