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Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells

Arsenic trioxide (As(2)O(3)) is a novel anticancer agent, which has been found to induce remission in acute promyelocytic leukaemic patients following daily intravenous administration. The therapeutic value of As(2)O(3) in other cancers is still largely unknown. Cytotoxic tests in a panel of cancer...

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Detalles Bibliográficos
Autores principales: Yang, C-H, Kuo, M-L, Chen, J-C, Chen, Y-C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374294/
https://www.ncbi.nlm.nih.gov/pubmed/10555748
http://dx.doi.org/10.1038/sj.bjc.6690766