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Cells shed from tumours show reduced clonogenicity, resistance to apoptosis, and in vivo tumorigenicity
The goal of this study was to compare growth characteristics of cells shed from a tumour with the native tumour cells. The human colon adenocarcinoma LS174T and its highly metastatic subline LS LiM 6 were grown as tissue-isolated tumours in nude mice and perfused to collect shed cells. The tumours w...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374305/ https://www.ncbi.nlm.nih.gov/pubmed/10555742 http://dx.doi.org/10.1038/sj.bjc.6690760 |