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Cells shed from tumours show reduced clonogenicity, resistance to apoptosis, and in vivo tumorigenicity

The goal of this study was to compare growth characteristics of cells shed from a tumour with the native tumour cells. The human colon adenocarcinoma LS174T and its highly metastatic subline LS LiM 6 were grown as tissue-isolated tumours in nude mice and perfused to collect shed cells. The tumours w...

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Detalles Bibliográficos
Autores principales:	Swartz, M A, Kristensen, C A, Melder, R J, Roberge, S, Calautti, E, Fukumura, D, Jain, R K
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374305/ https://www.ncbi.nlm.nih.gov/pubmed/10555742 http://dx.doi.org/10.1038/sj.bjc.6690760

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