Inhibiting tumorigenic potential by restoration of p16 in nasopharyngeal carcinoma

The p16 gene, encodes a key checkpoint protein p16 in the cell cycle, has been reported inactivation in a wide variety of human cancers. We have previously demonstrated high frequency of p16 alterations in primary nasopharyngeal carcinoma (NPC), xenografts and cell lines. The finding implied that in...

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Detalles Bibliográficos
Autores principales: Wang, G L, Lo, K W, Tsang, K S, Chung, N Y F, Tsang, Y S, Cheung, S T, Lee, J C K, Huang, D P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374319/
https://www.ncbi.nlm.nih.gov/pubmed/10584871
http://dx.doi.org/10.1038/sj.bjc.6690818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374319/
https://www.ncbi.nlm.nih.gov/pubmed/10584871
http://dx.doi.org/10.1038/sj.bjc.6690818

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