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Inhibiting tumorigenic potential by restoration of p16 in nasopharyngeal carcinoma
The p16 gene, encodes a key checkpoint protein p16 in the cell cycle, has been reported inactivation in a wide variety of human cancers. We have previously demonstrated high frequency of p16 alterations in primary nasopharyngeal carcinoma (NPC), xenografts and cell lines. The finding implied that in...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374319/ https://www.ncbi.nlm.nih.gov/pubmed/10584871 http://dx.doi.org/10.1038/sj.bjc.6690818 |