8-Cl-cAMP antagonizes mitogen-activated protein kinase activation and cell growth stimulation induced by epidermal growth factor

The growth factor-activated mitogenic pathways are often disregulated in tumour cells and, therefore, they can provide specific molecular targets for novel anti-tumour approaches. 8-Chloro-cAMP (8-Cl-cAMP), a synthetic cAMP analogue, is a novel anti-tumour agent that has recently undergone clinical...

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Detalles Bibliográficos
Autores principales: Budillon, A, Gennaro, E Di, Caraglia, M, Barbarulo, D, Abbruzzese, A, Tagliaferri, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374321/
https://www.ncbi.nlm.nih.gov/pubmed/10584873
http://dx.doi.org/10.1038/sj.bjc.6690820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374321/
https://www.ncbi.nlm.nih.gov/pubmed/10584873
http://dx.doi.org/10.1038/sj.bjc.6690820

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