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Analysis of radon-associated squamous cell carcinomas of the lung for ap53 gene hotspot mutation

Squamous cell lung carcinomas (SCC) from former employees of the Wismut uranium mining company (Saxony, Germany) were obtained from the Stollberg Archive in order to screen for p53 tumour suppressor gene codon 249 arg→met hotspot mutations, a putative molecular bio-dosimeter of alpha-particle (radon...

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Detalles Bibliográficos
Autores principales: Yang, Q, Wesch, H, Mueller, K-M, Bartsch, H, Wegener, K, Hollstein, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374385/
https://www.ncbi.nlm.nih.gov/pubmed/10732742
http://dx.doi.org/10.1054/bjoc.1999.0995