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Continuous low dose Thalidomide: a phase II study in advanced melanoma, renal cell, ovarian and breast cancer
To grow and metastasize, solid tumours must develop their own blood supply by neo-angiogenesis. Thalidomide inhibits the processing of mRNA encoding peptide molecules including tumour necrosis factor-alpha (TNF-α) and the angiogenic factor vascular endothelial growth factor (VEGF). This study invest...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374399/ https://www.ncbi.nlm.nih.gov/pubmed/10732751 http://dx.doi.org/10.1054/bjoc.1999.1004 |