Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status

Biological parameters influencing the response of human colorectal cancers (CRCs) to CPT-11, a topoisomerase 1 (top1) inhibitor, were investigated using a panel of nine CRCs xenografted into nude mice. CRC xenografts differed in their p53 status (wt or mut) and in their microsatellite instability ph...

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Detalles Bibliográficos
Autores principales: Bras-Gonçalves, R A, Rosty, C, Laurent-Puig, P, Soulié, P, Dutrillaux, B, Poupon, M-F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374412/
https://www.ncbi.nlm.nih.gov/pubmed/10732766
http://dx.doi.org/10.1054/bjoc.1999.1019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374412/
https://www.ncbi.nlm.nih.gov/pubmed/10732766
http://dx.doi.org/10.1054/bjoc.1999.1019

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