Cargando…
Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status
Biological parameters influencing the response of human colorectal cancers (CRCs) to CPT-11, a topoisomerase 1 (top1) inhibitor, were investigated using a panel of nine CRCs xenografted into nude mice. CRC xenografts differed in their p53 status (wt or mut) and in their microsatellite instability ph...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2000
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374412/ https://www.ncbi.nlm.nih.gov/pubmed/10732766 http://dx.doi.org/10.1054/bjoc.1999.1019 |