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Decreased GTPase activity of K- ras mutants deriving from human functional adrenocortical tumours
Our previous studies have shown that seven out of 15 patients with adrenocortical tumours contained K- ras gene mutation. In addition, the mutation type was a multiple-site mutation, and the hot spots were located at codons 15, 16, 18 and 31, which were different from those reported before (codons 1...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374427/ https://www.ncbi.nlm.nih.gov/pubmed/10737386 http://dx.doi.org/10.1054/bjoc.1999.1039 |