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Regulation of Sox9 activity by crosstalk with nuclear factor-κB and retinoic acid receptors
INTRODUCTION: Sox9 and p300 cooperate to induce expression of cartilage-specific matrix proteins, including type II collagen, aggrecan and link protein. Tumour necrosis factor (TNF)-α, found in arthritic joints, activates nuclear factor-κB (NF-κB), whereas retinoic acid receptors (RARs) are activate...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374456/ https://www.ncbi.nlm.nih.gov/pubmed/18182117 http://dx.doi.org/10.1186/ar2349 |