Regulation of Sox9 activity by crosstalk with nuclear factor-κB and retinoic acid receptors

INTRODUCTION: Sox9 and p300 cooperate to induce expression of cartilage-specific matrix proteins, including type II collagen, aggrecan and link protein. Tumour necrosis factor (TNF)-α, found in arthritic joints, activates nuclear factor-κB (NF-κB), whereas retinoic acid receptors (RARs) are activate...

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Detalles Bibliográficos
Autores principales: Rockel, Jason S, Kudirka, Julie C, Guzi, Andrew J, Bernier, Suzanne M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374456/
https://www.ncbi.nlm.nih.gov/pubmed/18182117
http://dx.doi.org/10.1186/ar2349

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