The role of aldosterone blockade in murine lupus nephritis

BACKGROUND: The purpose of this study was to examine the effect of aldosterone receptor blockade on the immunopathogenesis and progression of nephritis in the (NZB × NZW) F(1 )murine lupus model. METHODS: Female NZB/W F(1 )mice (11 weeks old) were treated daily with 25 or 50 mg/kg oral spironolacton...

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Detalles Bibliográficos
Autores principales: Monrad, Seetha U, Killen, Paul D, Anderson, Marc R, Bradke, Amanda, Kaplan, Mariana J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374470/
https://www.ncbi.nlm.nih.gov/pubmed/18197980
http://dx.doi.org/10.1186/ar2353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374470/
https://www.ncbi.nlm.nih.gov/pubmed/18197980
http://dx.doi.org/10.1186/ar2353

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