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The role of aldosterone blockade in murine lupus nephritis
BACKGROUND: The purpose of this study was to examine the effect of aldosterone receptor blockade on the immunopathogenesis and progression of nephritis in the (NZB × NZW) F(1 )murine lupus model. METHODS: Female NZB/W F(1 )mice (11 weeks old) were treated daily with 25 or 50 mg/kg oral spironolacton...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374470/ https://www.ncbi.nlm.nih.gov/pubmed/18197980 http://dx.doi.org/10.1186/ar2353 |