Inhibition of hyaluronan export reduces collagen degradation in interleukin-1 treated cartilage

BACKGROUND: Osteoarthrosis is characterized by cartilage erosion, proteolysis of aggrecan and collagen, and disturbed rates of synthesis of aggrecan and hyaluronan by chondrocytes, with hyaluronan over-production being an early reaction. We considered that inhibition of hyaluronan export might preve...

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Detalles Bibliográficos
Autores principales: Deiters, Barthold, Prehm, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374471/
https://www.ncbi.nlm.nih.gov/pubmed/18205921
http://dx.doi.org/10.1186/ar2357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374471/
https://www.ncbi.nlm.nih.gov/pubmed/18205921
http://dx.doi.org/10.1186/ar2357

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