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Inhibition of hyaluronan export reduces collagen degradation in interleukin-1 treated cartilage
BACKGROUND: Osteoarthrosis is characterized by cartilage erosion, proteolysis of aggrecan and collagen, and disturbed rates of synthesis of aggrecan and hyaluronan by chondrocytes, with hyaluronan over-production being an early reaction. We considered that inhibition of hyaluronan export might preve...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374471/ https://www.ncbi.nlm.nih.gov/pubmed/18205921 http://dx.doi.org/10.1186/ar2357 |