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Nuclear translocation of beta-catenin in colorectal cancer

Post-translational stabilization of beta-catenin through mutation of the adenomatous polyposis coli (APC) gene has been proposed as an early step in colorectal carcinogenesis. Beta-catenin may translocate from the cytoplasm to the nucleus, where it might serve as a transcriptional factor to stimulat...

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Detalles Bibliográficos
Autores principales: Kobayashi, M, Honma, T, Matsuda, Y, Suzuki, Y, Narisawa, R, Ajioka, Y, Asakura, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374509/
https://www.ncbi.nlm.nih.gov/pubmed/10817505
http://dx.doi.org/10.1054/bjoc.1999.1112