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Antagonists of growth hormone-releasing hormone (GH-RH) inhibit IGF-II production and growth of HT-29 human colon cancers

Insulin-like growth factors (IGFs) I and II are implicated in progression of various tumours including colorectal carcinomas. To interfere with the production of IGFs, we treated male nude mice bearing xenografts of HT-29 human colon cancer with various potent growth hormone-releasing hormone (GH-RH...

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Detalles Bibliográficos
Autores principales: Szepeshazi, K, Schally, A V, Groot, K, Armatis, P, Halmos, G, Hebert, F, Szende, B, Varga, J L, Zarandi, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374518/
https://www.ncbi.nlm.nih.gov/pubmed/10817510
http://dx.doi.org/10.1054/bjoc.2000.1223