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Effect of a fluorinated pyrimidine on cachexia and tumour growth in murine cachexia models: relationship with a proteolysis inducing factor

The fluorinated pyrimidine nucleoside, 5′-deoxy-5-fluorouridine (5′-dFUrd) has been shown to effectively attenuate the progress of cachexia in the murine adenocarcinomas MAC16 and colon 26 as well as in the human uterine cervical carcinoma xenograft, Yumoto. Although concomitant inhibition of tumour...

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Detalles Bibliográficos
Autores principales: Hussey, H J, Todorov, P T, Field, W N, Inagaki, N, Tanaka, Y, Ishitsuka, H, Tisdale, M J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374525/
https://www.ncbi.nlm.nih.gov/pubmed/10883668
http://dx.doi.org/10.1054/bjoc.2000.1278