Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport

The human multidrug transporter MDR1 P-glycoprotein and the multidrug resistance proteins MRP1 and MRP2 transport a range of cytotoxic drugs, resulting in multidrug resistance in tumour cells. To overcome this form of drug resistance in patients, several inhibitors (reversal agents) of these transpo...

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Detalles Bibliográficos
Autores principales: Evers, R, Kool, M, Smith, A J, Deemter, L van, Haas, M de, Borst, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374556/
https://www.ncbi.nlm.nih.gov/pubmed/10917553
http://dx.doi.org/10.1054/bjoc.2000.1260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374556/
https://www.ncbi.nlm.nih.gov/pubmed/10917553
http://dx.doi.org/10.1054/bjoc.2000.1260

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