Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

The multidrug resistance proteins MRP1 and MRP2 are members of the same subfamily of ATP-binding cassette transporters. Besides organic molecules conjugated to negatively charged ligands, these proteins also transport cytotoxic drugs for which no negatively charged conjugates are known to exist. In...

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Detalles Bibliográficos
Autores principales: Evers, R, Haas, M de, Sparidans, R, Beijnen, J, Wielinga, P R, Lankelma, J, Borst, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374564/
https://www.ncbi.nlm.nih.gov/pubmed/10917554
http://dx.doi.org/10.1054/bjoc.2000.1262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374564/
https://www.ncbi.nlm.nih.gov/pubmed/10917554
http://dx.doi.org/10.1054/bjoc.2000.1262

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