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Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

The multidrug resistance proteins MRP1 and MRP2 are members of the same subfamily of ATP-binding cassette transporters. Besides organic molecules conjugated to negatively charged ligands, these proteins also transport cytotoxic drugs for which no negatively charged conjugates are known to exist. In...

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Detalles Bibliográficos
Autores principales:	Evers, R, Haas, M de, Sparidans, R, Beijnen, J, Wielinga, P R, Lankelma, J, Borst, P
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2000
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374564/ https://www.ncbi.nlm.nih.gov/pubmed/10917554 http://dx.doi.org/10.1054/bjoc.2000.1262

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