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Characterization and modulation of drug resistance of human paediatric rhabdomyosarcoma cell lines

The role of multidrug resistance (MDR) and p53 functional status in the treatment of paediatric rhabdomyosarcoma is unclear. We have characterized a panel of seven human rhabdomyosarcoma cell lines for MDR and p53 phenotype. None of the cell lines had P-glycoprotein (P-gp) or multidrug resistance-re...

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Detalles Bibliográficos
Autores principales: Cocker, H A, Pinkerton, C R, Kelland, L R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374566/
https://www.ncbi.nlm.nih.gov/pubmed/10917549
http://dx.doi.org/10.1054/bjoc.2000.1273