Cargando…
Endothelin-1 from prostate cancer cells is enhanced by bone contact which blocks osteoclastic bone resorption
The causes for the propensity of metastasized prostate cancer cells to grow in bone and to induce osteoblastic lesions remain unresolved. Co-culture of human prostate cancer cell lines with bone slices was determined to increase the level of endothelin-1 (ET-1) mRNA and its production. ET-1 is an ej...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2000
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374574/ https://www.ncbi.nlm.nih.gov/pubmed/10917552 http://dx.doi.org/10.1054/bjoc.2000.1261 |