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Caffeine does not cause override of the G2/M block induced by UVc or gamma radiation in normal human skin fibroblasts

Caffeine has for many years been known to be involved in the sensitization of DNA to damage. One potential mechanism recently put forward is an override of the G2/M block induced by irradiation, which would leave the cells less time for DNA repair prior to mitosis. However, different cell types disp...

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Detalles Bibliográficos
Autores principales: Deplanque, G, Vincent, F, Mah-Becherel, M C M, Cazenave, J-P, Bergerat, J-P, Klein-Soyer, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374578/
https://www.ncbi.nlm.nih.gov/pubmed/10917550
http://dx.doi.org/10.1054/bjoc.2000.1259