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Fibrinogen decreases cardiomyocyte contractility through an ICAM-1-dependent mechanism

INTRODUCTION: Cardiomyocytes exposed to inflammatory processes express intracellular adhesion molecule-1 (ICAM-1). We investigated whether fibrinogen and fibrinogen degradation products, including D-dimer, could alter cardiomyocyte contractile function through interaction with ICAM-1 found on inflam...

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Detalles Bibliográficos
Autores principales: Boyd, John H, Chau, Edmond H, Tokunanga, Chiho, Bateman, Ryon M, Haljan, Greg, Davani, Ehsan Y, Wang, Yinjin, Walley, Keith R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374637/
https://www.ncbi.nlm.nih.gov/pubmed/18173852
http://dx.doi.org/10.1186/cc6213