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The rate of the founder Jewish mutations in BRCA1 and BRCA2 in prostate cancer patients in Israel
Inherited predisposition occurs in 5–10% of all prostate cancer (CaP) patients, but the genes involved in conferring genetic susceptibility remain largely unknown. Several lines of evidence indicate that germline mutations in BRCA1 and BRCA2 might be associated with an increased risk for CaP. Three...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374645/ https://www.ncbi.nlm.nih.gov/pubmed/10945492 http://dx.doi.org/10.1054/bjoc.2000.1249 |