Down-regulation of TGF- β 1 production restores immunogenicity in prostate cancer cells

The objective of this study is to determine if a non-immunogenic Dunning’s rat prostate cancer cell line, MATLyLu, can become immunogenic by reducing the endogenous production of TGF-β1. An expression construct containing a DNA sequence in an antisense orientation to TGF-β1 (TGF-β1 antisense) was st...

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Detalles Bibliográficos
Autores principales: Matthews, E, Yang, T, Janulis, L, Goodwin, S, Kundu, S D, Karpus, W J, Lee, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374659/
https://www.ncbi.nlm.nih.gov/pubmed/10945501
http://dx.doi.org/10.1054/bjoc.2000.1257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374659/
https://www.ncbi.nlm.nih.gov/pubmed/10945501
http://dx.doi.org/10.1054/bjoc.2000.1257

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