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Down-regulation of TGF- β 1 production restores immunogenicity in prostate cancer cells
The objective of this study is to determine if a non-immunogenic Dunning’s rat prostate cancer cell line, MATLyLu, can become immunogenic by reducing the endogenous production of TGF-β1. An expression construct containing a DNA sequence in an antisense orientation to TGF-β1 (TGF-β1 antisense) was st...
Autores principales: | Matthews, E, Yang, T, Janulis, L, Goodwin, S, Kundu, S D, Karpus, W J, Lee, C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374659/ https://www.ncbi.nlm.nih.gov/pubmed/10945501 http://dx.doi.org/10.1054/bjoc.2000.1257 |
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