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Expression of topoisomerase III α in normal and neoplastic tissues determined by immunohistochemistry using novel monoclonal antibody
Topoisomerases are nuclear enzymes that modulate the topological structure of DNA in order to facilitate cellular events such as replication and transcription. These enzymes are also the cellular targets of certain classes of chemotherapeutic agents termed topoisomerase poisons. A new human topoisom...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374664/ https://www.ncbi.nlm.nih.gov/pubmed/10945498 http://dx.doi.org/10.1054/bjoc.2000.1293 |