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Computational identification of the normal and perturbed genetic networks involved in myeloid differentiation and acute promyelocytic leukemia
BACKGROUND: Acute myeloid leukemia (AML) comprises a group of diseases characterized by the abnormal development of malignant myeloid cells. Recent studies have demonstrated an important role for aberrant transcriptional regulation in AML pathophysiology. Although several transcription factors (TFs)...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374711/ https://www.ncbi.nlm.nih.gov/pubmed/18291030 http://dx.doi.org/10.1186/gb-2008-9-2-r38 |