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Computational identification of the normal and perturbed genetic networks involved in myeloid differentiation and acute promyelocytic leukemia

BACKGROUND: Acute myeloid leukemia (AML) comprises a group of diseases characterized by the abnormal development of malignant myeloid cells. Recent studies have demonstrated an important role for aberrant transcriptional regulation in AML pathophysiology. Although several transcription factors (TFs)...

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Detalles Bibliográficos
Autores principales:	Chang, Li Wei, Payton, Jacqueline E, Yuan, Wenlin, Ley, Timothy J, Nagarajan, Rakesh, Stormo, Gary D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374711/ https://www.ncbi.nlm.nih.gov/pubmed/18291030 http://dx.doi.org/10.1186/gb-2008-9-2-r38

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