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Finding exonic islands in a sea of non-coding sequence: splicing related constraints on protein composition and evolution are common in intron-rich genomes

BACKGROUND: In mammals, splice-regulatory domains impose marked trends on the relative abundance of certain amino acids near exon-intron boundaries. Is this a mammalian particularity or symptomatic of exonic splicing regulation across taxa? Are such trends more common in species that a priori have a...

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Detalles Bibliográficos
Autores principales: Warnecke, Tobias, Parmley, Joanna L, Hurst, Laurence D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374712/
https://www.ncbi.nlm.nih.gov/pubmed/18257921
http://dx.doi.org/10.1186/gb-2008-9-2-r29