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Finding exonic islands in a sea of non-coding sequence: splicing related constraints on protein composition and evolution are common in intron-rich genomes
BACKGROUND: In mammals, splice-regulatory domains impose marked trends on the relative abundance of certain amino acids near exon-intron boundaries. Is this a mammalian particularity or symptomatic of exonic splicing regulation across taxa? Are such trends more common in species that a priori have a...
Autores principales: | Warnecke, Tobias, Parmley, Joanna L, Hurst, Laurence D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374712/ https://www.ncbi.nlm.nih.gov/pubmed/18257921 http://dx.doi.org/10.1186/gb-2008-9-2-r29 |
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