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Concordant Gene Expression in Leukemia Cells and Normal Leukocytes Is Associated with Germline cis-SNPs

The degree to which gene expression covaries between different primary tissues within an individual is not well defined. We hypothesized that expression that is concordant across tissues is more likely influenced by genetic variability than gene expression which is discordant between tissues. We qua...

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Detalles Bibliográficos
Autores principales: French, Deborah, Yang, Wenjian, Hamilton, Leo H., Neale, Geoffrey, Fan, Yiping, Downing, James R., Cox, Nancy J., Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374895/
https://www.ncbi.nlm.nih.gov/pubmed/18478092
http://dx.doi.org/10.1371/journal.pone.0002144